Skip Nav | Home | Mobile | Editorial Guidelines | Mission Statement | About Us | Contact | Help | Security | Support Us

World

Biopirates: Bayer earns $379m from diabetes drug

CBGnetwork | 19.02.2006 09:48 | Bio-technology | Globalisation | Health | Cambridge | World

Bacteria harvested from Kenya are being used by a global pharmaceutical company to manufacture a multi-million dollar diabetes drug, although the country is not making a shilling from the entire enterprise, a dossier prepared by a respectable American think-tank says.



East African, February 13, 2006

Biopirates: Bayer earns $379m from diabetes drug

Bacteria harvested from Kenya are being used by a global pharmaceutical company to manufacture a multi-million dollar diabetes drug, although the country is not making a shilling from the entire enterprise, a dossier prepared by a respectable American think-tank says.

Sale of the drug, Glucobay, hit $379 million in the 12 months to December 31, 2004, making it one of the leading brands in the world. Glucobay, scientifically known as acarbose, is sold by the German pharmaceutical giant Bayer.

According to the report Out of Africa: Mysteries of Access and Benefit Sharing - published jointly by the Washington-based Edmonds Institute and the African Centre for Biosafety, in 1995 - five years after Glucobay first hit the European market but one year before it was sold in the lucrative American market, Bayer filed for a patent on a new way to manufacture the drug. The patent was subsequently approved in Europe, America and Australia.

Perusal of the patent application for the new method of manufacturing Glucobay revealed that it involved the use of a bacterium called Actinoplanes SE 50, which is found in water masses around Ruiru, near Nairobi.

"In 2001, in an article in the Journal of Bacteriology, a group of Bayer scientists and German academics confirmed that SE 50 was being used to manufacture acarbose," the report by the Institute says. "Although their paper did not mention Kenya, it did say that 'the oral antidiabetic agent is produced by fermentation of actinomyecete Actinoplanes species strain SE 50.'"
Apart from Kenya, the Edmonds report details extraction of natural resources from sub-Saharan Africa that have been commercialised for medicinal or cosmetic purposes, earning their patent holders hundreds of millions of dollars without compensating the communities from where they were extracted, even though the communities had been using them for centuries.

The companies involved read like a roll-call of the top players in the global medicines and cosmetics market, and include GlaxoSmithKline, Merck Sharp & Dohme, Pfizer and French cosmetic giant Dior. (By DAGI KIMANI)


Excerpt from "Out of Africa: Mysteries of Access and Benefit Sharing", page 11
Diabetes Drug Produced by a Microbe

Many of those who suffer from Type II diabetes can thank a microbe from Kenya's Lake Ruiru for a drug that improves their lives. Type II diabetics frequently take acarbose, a drug better known by its trade names Precose (in the US and Canada) and Glucobay (in Europe and elsewhere). (3)
The drug is an "alpha glucosidase inhibitor", meaning that it works by regulating absorption of glucose into the bloodstream, thereby preventing potentially dangerous spikes of glucose ("blood sugar").
Acarbose is sold by the German pharmaceutical giant, Bayer. How is it made? In 1995, five years after Glucobay was commercialized in Europe and one year before it was released in North America, Bayer filed for patent on a new way to manufacture the product. The patent application, which subsequently issued in Europe, the US, and Australia, (4) reveals that an Actinoplanes sp. bacteria strain called SE 50 had unique genes that enable the biosynthesis of acarbose in fermentors. The strain comes from Kenya's Lake Ruiru.
In 2001, in an article in the Journal of Bacteriology, a group of Bayer scientists and German academics confirmed that SE 50 was being used to manufacture acarbose. (5) In the article, they described manufacture of acarbose and related compounds. Although their paper did not mention Kenya or Africa, it did say that "The oral antidiabetic agent [acarbose] is produced by fermentation of the actinomycete Actinoplanes sp. strain SE50."
SE50 is the same strain that was identified as Kenyan in the patent application filed six years before.
In 2004, Bayer sales of acarbose totaled €278 million (US $379 million, as of 31 Dec 2004). (6) I could find no evidence of a benefit-sharing agreement related to this extremely valuable microbe.

distributed by: Coalition against BAYER-dangers (Germany)
www.CBGnetwork.org
 CBGnetwork@aol.com
Fax: (+49) 211-333 940 Tel: (+49) 211-333 911
please send an e-mail for receiving the English newsletter Keycode BAYER free of charge. German/Italian/French/Spanish newsletters also available.

Advisory Board
Prof. Juergen Junginger, designer, Krefeld,
Prof. Dr. Juergen Rochlitz, chemist, former member of the German Bundestag, Burgwald
Wolfram Esche, attorney-at-law, Cologne
Dr. Sigrid Müller, pharmacologist, Bremen
Eva Bulling-Schroeter, member of the German Bundestag, Ingolstadt
Prof. Dr. Anton Schneider, construction biologist, Neubeuern
Dorothee Sölle, theologian, Hamburg (died 2003)
Dr. Janis Schmelzer, historian, Berlin
Dr. Erika Abczynski, pediatrician, Dormagen

CBGnetwork
- e-mail: CBGnetwork@aol.com
- Homepage: http://www.CBGnetwork.org

Publish

Publish your news

Do you need help with publishing?

/regional publish include --> /regional search include -->

World Topics

Afghanistan
Analysis
Animal Liberation
Anti-Nuclear
Anti-militarism
Anti-racism
Bio-technology
Climate Chaos
Culture
Ecology
Education
Energy Crisis
Fracking
Free Spaces
Gender
Globalisation
Health
History
Indymedia
Iraq
Migration
Ocean Defence
Other Press
Palestine
Policing
Public sector cuts
Repression
Social Struggles
Technology
Terror War
Workers' Movements
Zapatista

Kollektives

Birmingham
Cambridge
Liverpool
London
Oxford
Sheffield
South Coast
Wales
World

Other UK IMCs
Bristol/South West
London
Northern Indymedia
Scotland

Server Appeal Radio Page Video Page Indymedia Cinema Offline Newsheet

secure Encrypted Page

You are viewing this page using an encrypted connection. If you bookmark this page or send its address in an email you might want to use the un-encrypted address of this page.

If you recieved a warning about an untrusted root certificate please install the CAcert root certificate, for more information see the security page.

IMCs


www.indymedia.org

Projects
print
radio
satellite tv
video

Africa

Europe
antwerpen
armenia
athens
austria
barcelona
belarus
belgium
belgrade
brussels
bulgaria
calabria
croatia
cyprus
emilia-romagna
estrecho / madiaq
galiza
germany
grenoble
hungary
ireland
istanbul
italy
la plana
liege
liguria
lille
linksunten
lombardia
madrid
malta
marseille
nantes
napoli
netherlands
northern england
nottingham imc
paris/île-de-france
patras
piemonte
poland
portugal
roma
romania
russia
sardegna
scotland
sverige
switzerland
torun
toscana
ukraine
united kingdom
valencia

Latin America
argentina
bolivia
chiapas
chile
chile sur
cmi brasil
cmi sucre
colombia
ecuador
mexico
peru
puerto rico
qollasuyu
rosario
santiago
tijuana
uruguay
valparaiso
venezuela

Oceania
aotearoa
brisbane
burma
darwin
jakarta
manila
melbourne
perth
qc
sydney

South Asia
india


United States
arizona
arkansas
asheville
atlanta
Austin
binghamton
boston
buffalo
chicago
cleveland
colorado
columbus
dc
hawaii
houston
hudson mohawk
kansas city
la
madison
maine
miami
michigan
milwaukee
minneapolis/st. paul
new hampshire
new jersey
new mexico
new orleans
north carolina
north texas
nyc
oklahoma
philadelphia
pittsburgh
portland
richmond
rochester
rogue valley
saint louis
san diego
san francisco
san francisco bay area
santa barbara
santa cruz, ca
sarasota
seattle
tampa bay
united states
urbana-champaign
vermont
western mass
worcester

West Asia
Armenia
Beirut
Israel
Palestine

Topics
biotech

Process
fbi/legal updates
mailing lists
process & imc docs
tech